INTEGRATED PROTEOMIC AND METABOLOMIC ANALYSIS REVEALS NADH-MEDIATED TCA ENERGY METABOLISM DISORDER IN CHRONIC PROGRESSIVE HEART FAILURE
نویسندگان
چکیده
منابع مشابه
Integrated proteomic and metabolomic analysis reveals the NADH-mediated TCA cycle and energy metabolism disorders based on a new model of chronic progressive heart failure.
BACKGROUND Despite major advances in the treatment of heart failure (HF), it remains the major cause of mortality and morbidity worldwide. Experimental models of HF typically utilize acute myocardial infarction. However, the majority of clinical HFs occur gradually by a chronic progressive mechanism. Thus, more relevant models are required to aid identification, quantification, and characteriza...
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ژورنال
عنوان ژورنال: Heart
سال: 2012
ISSN: 1355-6037,1468-201X
DOI: 10.1136/heartjnl-2012-302920b.12